| 摘要 |
The present invention embraces essentially pure human FSH receptor, or a fragment or mutant thereof which binds FSH, DNA encoding said receptor, fragment or mutant, expression vectors comprising said DNA, cells transfected with said expres-sion vectors, and methods of producing said receptor, fragment or mutant by culturing said transfected cells. The present inven-tion also includes pharmaceutical compositions comprising said receptor, fragment or mutant, as well as methods of treating pa-tients with such compositions to reduce endogenous FSH bioactivity. An improved assay for human FSH using the receptor, fragment or mutant of the present invention is also disclosed.
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