发明名称 |
Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them |
摘要 |
Compounds of structure (I) having histone deacetylase (HDAC) inhibitor activity are described. The compounds are chemically characterised by the presence of hydroxamic acid, with zinc as chelator, and an aromatic nucleus connected by a linker in which either a bicyclic aromatic system or a piperidino ring are present.
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申请公布号 |
US2008207694(A1) |
申请公布日期 |
2008.08.28 |
申请号 |
US20060886160 |
申请日期 |
2006.03.14 |
申请人 |
ROSSI CRISTINA;PORCELLONI MARINA;D ANDREA PIERO;FATTORI DANIELA;MARASTONI ELENA |
发明人 |
ROSSI CRISTINA;PORCELLONI MARINA;D'ANDREA PIERO;FATTORI DANIELA;MARASTONI ELENA |
分类号 |
A61K31/445;C07D211/32 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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