The present invention discloses and claims chimeric virus like particles (VLPs) that express and/or contains Newcastle disease matrix protein. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising chimeric VLPs of the inventions. The invention also includes methods of making and administrating chimeric VLPs to vertebrates, including methods of inducing immunity to infections.
申请公布号
WO2008103819(A2)
申请公布日期
2008.08.28
申请号
WO2008US54570
申请日期
2008.02.21
申请人
NOVAVAX, INC.;MAHMOOD, KUTUB;SMITH, GALE;PUSHKO, PETER