发明名称 GENE TRANSFER AGENT
摘要 PROBLEM TO BE SOLVED: To provide a gene transfer agent which can transfer a gene to a vascular endothelial cell. SOLUTION: This gene transfer agent is produced by adsorbing or complexing a peptide having an RGD sequence to a complex of a nucleic acid with a polymer obtained by introducing a plurality of polymer chains as substituents to an aromatic ring. The gene transfer agent, wherein the aromatic ring comprises a 5 to 8C aromatic, monoring or condensed ring. The gene transfer agent, wherein the polymer chain is a polyacrylamide-based polymer block chain or a polyacrylate-based polymer block chain. COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008195682(A) 申请公布日期 2008.08.28
申请号 JP20070034890 申请日期 2007.02.15
申请人 NATIONAL CARDIOVASCULAR CENTER;BRIDGESTONE CORP 发明人 NAKAYAMA YASUHIDE;NEMOTO YASUSHI
分类号 A61K47/48;A61K47/32;A61K48/00;C12N15/09 主分类号 A61K47/48
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