发明名称 ADENOSINE A1 RECEPTOR AGONISTS
摘要 <p>A compound of formula (I), wherein R2 represents C1-3alkyl, halogen or hydrogen; R3 represents straight or branched alkyl group of 1-6 carbon atoms; with the proviso that, when R3 represents C1-3alkyl, R2 represents C1-3alkyl, R1 cannot represent phenyl optionally substituted by one or more substituents selected from halogen, C1-3alkyl, trifluoromethyl, nitro, cyano, -CO2Rc, - CONRcRd, -CORc, -SORe, -SO2Re, -SO3H, -SO2NRcRd, -ORc, -NHSO2Re, -NHCORc and - NRcRd; and salts and solvates thereof, in particular, physiologically acceptable solvates and salts thereof. These compounds are agonists at the Adenosine A1 receptor.</p>
申请公布号 CA2309202(C) 申请公布日期 2008.06.17
申请号 CA19982309202 申请日期 1998.11.06
申请人 GLAXO GROUP LIMITED 发明人 PENNELL, ANDREW MICHAEL KENNETH;ELDRED, COLIN DAVID
分类号 C07H19/167;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61P9/00;A61P25/00;A61P43/00;C07H19/16 主分类号 C07H19/167
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