| 摘要 |
Abuse-proofed, thermoformed dosage form (C1) comprises an active ingredient with abuse potential (A) optionally together with physiologically acceptable auxiliary substances (B), synthetic or natural polymer (P1) and optionally at least one wax (D). (P1) Exhibits a breaking strength of at least 500 N. An independent claim is included for: preparation of (C1) which comprises mixing components (A), (B), (P1) and the other optional components, followed by pressing the resultant mixture, optionally after granulation (preferably by a melt process), to yield (C1) with preceding, simultaneous, or subsequent exposure to heat. ACTIVITY : None given MECHANISM OF ACTION : None given. |
