发明名称 |
Treatment with immunoregulatory t cells |
摘要 |
Methods and compositions are provided for the treatment of an autoimmune disease. The methods include administering immunoregulatory T cells (T<SUB>regs</SUB>) to patients. The therapeutic T<SUB>regs </SUB>can express the CD25, CD4, and/or ICOS antigens. The therapeutic T cells can be CD25<SUP>+</SUP> ICOS<SUP>+</SUP>, CD4<SUP>+</SUP>ICOS<SUP>+</SUP>, and/or CD25<SUP>+</SUP> CD4<SUP>+</SUP> ICOS<SUP>+</SUP>, and they can be provided by a donor. |
申请公布号 |
US2007110710(A1) |
申请公布日期 |
2007.05.17 |
申请号 |
US20040578797 |
申请日期 |
2004.11.05 |
申请人 |
NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. |
发明人 |
FOSS FRANCINE M.;XIE YONG |
分类号 |
A61K38/19;A01N63/00;A61K35/14;C12N;C12N5/00;C12N5/06 |
主分类号 |
A61K38/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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