摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a new efficient method for transfering a nucleic acid into cells, and a culturing subatrate used for the method. <P>SOLUTION: This method for transfering the nucleic acid into the cells is provided by immobilizing a polyion complex of the nucleic acid with a cationized polysaccharide together with a cell adhesion promoter for cell adhesion to the cell-culturing substrate firmly under a physiological condition familiar with the cells on the culturing substrate, and culturing the cells on the culturing substrate so as to incorporate the nucleic acid into the cells. The culturing substrate is provided by immobilizing the polyion complex of the nucleic acid with the cationized polysaccharide and the cell adhesion promoter. <P>COPYRIGHT: (C)2007,JPO&INPIT</p> |