Generation of artificial binding proteins on the basis of ubiquitin proteins

摘要

The invention relates to modified proteins of the superfamily of "ubiguitin-like proteins", proteins that have a ubiguitin-like fold and fragments or fusion proteins thereof. As a result of said modification, the proteins have a binding affinity with respect to a predetermined binding partner that did not exist previously. The invention also relates to a method for the production and utilization of said proteins.