摘要 |
<p>The present invention relates to a process for the manufacture of iohexol, 5-[N- (2,3-dihydroxypropyl) -acetamido]-N,N'-bis(2,3 - dihydroxypropyl)-2,4,6-triiodoisophtalamide by selecting a solvent comprising a C1-C5-monoalkylether of a C3-C 10 alkylene-glycol.</p> |