| 发明名称 |
PDZ DOMAIN INTERACTIONS AND LIPID RAFTS |
| 摘要 |
Methods for modulating immune cell signaling are provided. In general such methods involve modulating an interaction between a PDZ protein and a PDZ ligand protein whose interaction affects the composition and/or distribution of lipid rafts in an immune cell. Modulators that enhance or inhibit such interactions are also disclosed, as well as methods of screening for such modulators.
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| 申请公布号 |
US2008166736(A1) |
申请公布日期 |
2008.07.10 |
| 申请号 |
US20070674034 |
申请日期 |
2007.02.12 |
| 申请人 |
ARBOR VITA CORPORATION;THE GENERAL HOSPITAL CORPORATION |
发明人 |
LU PETER S.;DIAZ-SARMIENTO CHAMORRO SOMOZA;SEED BRIAN;XAVIER RAMNIK;IRVING BRAYAN ALLEN |
| 分类号 |
G01N33/53;C12N5/00;G01N33/564;G01N33/566 |
主分类号 |
G01N33/53 |
| 代理机构 |
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