发明名称 |
NEW SOLID FORMS OF [4-(3-FLUORO-5-TRIFLUOROMETHYL-PYRIDIN-2-YL)-PIPERAZIN-1-YL-[5-METHANESULFONYL-2-((S)-2,2,2-TRIFLUORO-1-METHYL-ETHOXY)-PHENYL]-METHANONE |
摘要 |
The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) wherein R<SUP>1 </SUP>to R<SUP>5</SUP>, R<SUP>5'</SUP>, X, Y and A are as defined in the specification.
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申请公布号 |
US2008167333(A1) |
申请公布日期 |
2008.07.10 |
申请号 |
US20070955440 |
申请日期 |
2007.12.13 |
申请人 |
BISSANTZ CATERINA;GRUNDSCHOBER CHRISTOPHE;MASCIADRI RAFFAELLO;RATNI HASANE;ROGERS-EVANS MARK;SCHNIDER PATRICK |
发明人 |
BISSANTZ CATERINA;GRUNDSCHOBER CHRISTOPHE;MASCIADRI RAFFAELLO;RATNI HASANE;ROGERS-EVANS MARK;SCHNIDER PATRICK |
分类号 |
C07D487/10;A61K31/438 |
主分类号 |
C07D487/10 |
代理机构 |
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代理人 |
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地址 |
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