摘要 |
The present invention relates to a process for the manufacturing of subst ituted 3- amino-tetrahydrofuran-3-carboxylic acid amides of general formula (I) and their precursors in high optical purity to the precursors of the syn thesis of substituted S-Amino-tetrahydrofuran-S-carboxylic acid amides of ge neral formula (I) in high optical purity, and to the tautomers, enantiomers, diastereomers, mixtures and salts of substituted 3-amino- tetrahydrofuran-3 -carboxylic acid amides of general formula (I) in high optical purity, parti cularly the physiologically acceptable salts thereof with inorganic or organ ic acids or bases, which have valuable properties.
|
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
PFAU, ROLAND;PRIEPKE, HENNING;SCHULER-METZ, ANNETTE;KRISHNAMURTHY, DHILEEPKUMAR;SIEGER, PETER;SENANAYAKE, CHRIS H.;HAN, ZHENGXU;GERLACH, KAI;WIENEN, WOLFGANG;TANG, WENJUN;YEE, NATHAN K.;XU, YIBO;MATTHES, BURKHARD;NAR, HERBERT |