发明名称 ANALOGUE OF MAPKK NUCLEAR EXPORT-INHIBITING SUBSTANCE, PEUMUSOLIDE A AND ITS USE
摘要 <P>PROBLEM TO BE SOLVED: To provide an analogue of peumusolide A capable of exhibiting MAPKK nuclear export-inhibiting activities excellent in NES independency, and pharmaceuticals such as a carcinostatic and the like, foods and drinks, supplements and biochemical reagents using the same. <P>SOLUTION: The analogue of peumusolide A is represented by formula (I). R is -(CH<SB>2</SB>)<SB>6</SB>CH<SB>3</SB>in compound 1, and -(CH<SB>2</SB>)<SB>6</SB>CH<SB>2</SB>OH in compound 2. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008201751(A) 申请公布日期 2008.09.04
申请号 JP20070041604 申请日期 2007.02.22
申请人 OSAKA UNIV 发明人 MURAKAMI KEIJU;TAMURA OSAMU
分类号 C07D307/60;A23L1/30;A61K31/341;A61P35/00;A61P43/00 主分类号 C07D307/60
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