摘要 |
<P>PROBLEM TO BE SOLVED: To provide an analogue of peumusolide A capable of exhibiting MAPKK nuclear export-inhibiting activities excellent in NES independency, and pharmaceuticals such as a carcinostatic and the like, foods and drinks, supplements and biochemical reagents using the same. <P>SOLUTION: The analogue of peumusolide A is represented by formula (I). R is -(CH<SB>2</SB>)<SB>6</SB>CH<SB>3</SB>in compound 1, and -(CH<SB>2</SB>)<SB>6</SB>CH<SB>2</SB>OH in compound 2. <P>COPYRIGHT: (C)2008,JPO&INPIT |