发明名称 Cyclohexenone compounds from Antrodia Camphorata for use in the treatment of liver disease
摘要 A compound of formula (I) as defined therein can be obtained from Antrodia camphorata and finds use in liver protection, in particular 4-hydroxy-2,3-dimethoxy-6-methyl- 5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone. The compound helps to alleviate liver injury and fibrosis induced by chemicals and reduces the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). By increasing the content of glutathione peroxidase (GSHPx) and catalase (CAT), the said cyclohexenone reduces liver damage and oxidative pressure caused by free radicals and also enhances antioxidant ability. Pharmaceutical compositions comprising such compounds may also be prepared.
申请公布号 GB2450189(A) 申请公布日期 2008.12.17
申请号 GB20070024748 申请日期 2007.12.19
申请人 GOLDEN BIOTECHNOLOGY CORPORATION 发明人 SHENG-YUN LIU;MAO-TIEN KUO;WU-CHE WEN
分类号 A61K31/122;A61P1/16 主分类号 A61K31/122
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