发明名称 TREATMENT OF PAIN DISORDERS WITH TRANS 4-(3,4-DICHLOROPHENYL)-1,2 ,3,4-TETRAHYDRO-1-NAPHTHALENAMINE AND ITS FORMAMIDE.
摘要 <p>Treatment of pain disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]for mamide, which are also useful in treatment of pain disorders.</p>
申请公布号 MX2008015048(A) 申请公布日期 2008.12.10
申请号 MX20080015048 申请日期 2007.03.30
申请人 SEPRACOR INC. 发明人 PAUL TARANTINO;UNA CAMPBELL;LARRY BUSH
分类号 A61K31/135;A61K31/165;A61P25/00;A61P25/02 主分类号 A61K31/135
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