SKIN AND MUSCLE-TARGETED GENE THERAPY BY PULSED ELECTRICAL FIELD
摘要
The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
申请公布号
EP1100579(A4)
申请公布日期
2008.12.10
申请号
EP19990933937
申请日期
1999.07.13
申请人
GENETRONICS, INC.
发明人
DEV, NAGENDU B.;HOFMANN, GUNTER, A.;NOLAN, EDWARD;RABUSSAY, DIETMAR;TONNESSEN, ARNT;WIDERA, GEORG;ZHANG, LEI