| 摘要 |
A tablet for insertion into a vagina including 0.01 to 500 mg of a vagina l medication, such as a microbicide, such as cellulose acetate 1,2- benzened icarboxylate (CAP); 100 to 500 mg of mannitol powder; 50 to 300 mg of inert microcrystalline cellulose; 10 to 80 mg of hydroxypropyl methylcellulose; 50 to 250 mg of glycerol and optionally 2 to 4 mg of at least one preservative which protects against microbicidal contamination and discourages the growt h of yeast in the vagina. The tablet which includes CAP as the vaginal medic ation is vaginally administered before coitus in methods for preventing the sexual transmission of HIV- 1, HIV-2, herpesvirus, or an infection caused by Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Haemop hilus ducreyi or Treponema pallidum. The tablet which includes CAP as the va ginal medication is vaginally administered to prevent or treat bacterial vag inosis.
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