PEPTIDES DERIVED FROM PROTEINS OF THE INSULIN SUPER-FAMILY

摘要

The present invention relates to peptides derived from members of the insulin super-family. The peptides preferably bind and modify the activation status of receptors of proteins of the insulin super-family. The invention also relates to a pharmaceutical composition containing a compound comprising one or more of the peptides capable of promoting cell differentiation and/or modulating neuronal plasticity and/or proliferation of neural cells, and/or modulating survival and/or regeneration of cells expressing a receptor of a protein of the insulin super-family. The peptides may further be used to treat conditions affecting the peripheral and/or the central nervous system and/or muscles and other tissues or for treatment of normal, degenerated or damaged cells which express receptors of one or more proteins of the insulin super-family.