SOLUBLE VIRUS-SPECIFIC T-CELL RECEPTOR COMPOSITIONS

摘要

Compositions and methods for diagnosing a viral infection and methods of inhibiting such an infection are described. The methods are based on the identification of T-cell receptor gene sequences from cytotoxic T cell clones that are specific for HIV-I or HCV. Soluble T-cell receptor compositions that bind to HLA class I-restricted of HIV and HCV pathogens were identified and constructed.