发明名称 |
MALT1 SPECIFIC CLEAVAGE IN ASSAY AND SCREENING METHOD |
摘要 |
The present invention is based on the surprising finding of a proteolytic cleavage function of human Malt1. More particularly, the present invention relates to enzyme and screening assays, methods for assessing cleaving activity, methods for screening, isolated polypeptides, antibodies and inhibitors of Malt1. The present invention also relates to the use of Malt1 as a proteolytic enzyme and the use of compounds comprising a peptide comprising an amino acid sequence according to any one of SEQ ID NO: 1-47 as substrates susceptible for specific proteolytic cleavage. |
申请公布号 |
WO2008146259(A2) |
申请公布日期 |
2008.12.04 |
申请号 |
WO2008IB52122 |
申请日期 |
2008.05.30 |
申请人 |
UNIVERSITY OF LAUSANNE;THOME, MARGOT;REBEAUD, FABIEN;HAILFINGER, STEPHAN |
发明人 |
THOME, MARGOT;REBEAUD, FABIEN;HAILFINGER, STEPHAN |
分类号 |
G01N33/573;C12Q1/37 |
主分类号 |
G01N33/573 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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