摘要 |
A reference plant which has been selected to not express a medicinally active compounds but expresses most other non medicinally active compounds present in the therapeutically active comparator plant is disclosed. The plant can be used to generate a reference extract with a reference chemical profile that resembles that of the comparator plant without the active compound and therefore may be used as a placebo. In an exemplifying embodiment the medicinal compounds, which are "knocked out", are one or more cannabinoids and the plant is a cannabis, Cannabis sativa, plant. A method for producing the reference plant, extracts free of a medicinally active compound or group of compounds obtained therefrom and their use. More particularly, the novel reference plant is a plant derived from a comparator plant. |