发明名称 |
MULTI-DOSE CONCENTRATE ESMOLOL WITH BENZYL ALCOHOL |
摘要 |
Disclosed are concentrate esmolol injection essentially free from other related esters of esmolol and diluted esmolol compositions. The concentrate esmolol formulation includes from about 25-1000 mg/ml of esmolol and about 1-25% w/v of benzyl alcohol and the combination thereof. The compositions can also be used as multi-dose compositions. The present invention also discloses diluted, ready-to-use compositions of esmolol prepared by dilution of the present invention concentrates. Also disclosed are methods of making and using the ready-to-use compositions of the present invention.
|
申请公布号 |
US2008293810(A1) |
申请公布日期 |
2008.11.27 |
申请号 |
US20070752103 |
申请日期 |
2007.05.22 |
申请人 |
TIWARI DEEPAK;OWOO GEORGE;NAYAK REKHA;BURHOP KENNETH E |
发明人 |
TIWARI DEEPAK;OWOO GEORGE;NAYAK REKHA;BURHOP KENNETH E. |
分类号 |
A61K31/24;A61P9/00;C07C229/02 |
主分类号 |
A61K31/24 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|