LENTIVIRUS PSEUDOTYPED WITH INFLUENZA HEMAGGLUTININ AND METHODS OF USE
摘要
Highly effective pseudotyping of lentiviral vector with influenza HA, NA and M2 packaging gene constructs at the proper ratios. Lentivirus vector pseudotyped with influenza HA, especially pseudotyped with H5 and neuraminidase. Methods of inducing immune responses to influenza antigens or for transducing genes into cells to which influenza antigens bind using such lentivirus vectors. Methods for screening drugs which inhibit influenza infection using lentivirus pseudotyped with HA.
申请公布号
WO2008087563(A3)
申请公布日期
2008.11.27
申请号
WO2008IB01097
申请日期
2008.01.02
申请人
INSTITUT PASTEUR OF SHANGHAI;ZHOU, PAUL;TSAI, CHEGUO;TOYADA, TETSUYA;BUCHY, PHILIPPE
发明人
ZHOU, PAUL;TSAI, CHEGUO;TOYADA, TETSUYA;BUCHY, PHILIPPE