| 摘要 |
A living animal body including a human, afflicted with periventricular leukomalacia comprises administering to the living animal body, an amount of agomelatine or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, or its hydrate, crystalline form, or addition salt with acid or base that is effective for treatment of periventricular leukomalacia. The agomelatine is in crystalline form II. ACTIVITY : Cerebroprotective; Vasotropic. MECHANISM OF ACTION : Melatoninergic system receptor agonist; 5-HT-2C receptor antagonist. |
