发明名称 |
Method for decoloring human serum albumin |
摘要 |
<p>A method for decoloring a recombinant human serum albumin by treating the albumin with a reducing agent is disclosed. Also, a method for decoloring a recombinant human serum albumin by treating the albumin with a method removing free polysaccharides with a cation exchanger followed by heat treatment is disclosed. The present invention provides a recombinant human serum albumin, coloring of which is fully suppressed by preventing binding of certain coloring components, which are contained in the raw materials or contaminants secreted by a microorganism, to human serum albumin so as not to cause coloring of the human serum albumin.</p> |
申请公布号 |
EP0658569(B2) |
申请公布日期 |
2008.11.26 |
申请号 |
EP19940119966 |
申请日期 |
1994.12.16 |
申请人 |
MITSUBISHI PHARMA CORPORATION |
发明人 |
OHTANI, WATARU;FURUHATA, NAOTO;SUMI, AKINORI;NODA, MUNEHIRO;OHMURA, TAKAO |
分类号 |
C07K14/765;C12P21/00;A61K38/16;A61P7/00;C07K1/14;C07K1/20;C07K14/76;C12N15/00;C12R1/84 |
主分类号 |
C07K14/765 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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