发明名称 Direct aminolysis
摘要 In some aspects, the present invention provides a method of preparing a compound of the formula (I) comprising reacting a mesylate compound of the formula (II) by direct aminolysis with a reagent comprising ammonia. The reaction is preferably carried out in a solvent, such as an alcohol, and is preferably carried out in a sealed vessel such as a Parr reactor or the like.
申请公布号 ZA200801047(B) 申请公布日期 2008.11.26
申请号 ZA20080001047 申请日期 2008.01.31
申请人 PFIZER PRODUCTS INC. 发明人 LI, ZHENGONG BRYAN
分类号 C07C;C07D 主分类号 C07C
代理机构 代理人
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