发明名称 |
Vaginal pharmaceutical compositions and methods for preparing them |
摘要 |
Vaginal pharmaceutical compositions are described. These compositions contain (i) an active pharmaceutical ingredient selected from the group consisting of antimicrobial imidazoles and mixtures thereof, and (ii) a polysaccharide, wherein the pH of the composition is greater than 4.25 and less than about 8. In particularly preferred compositions, the active pharmaceutical ingredient includes metronidazole and the polysaccharide includes hypromellose. These compositions can be applied to vaginal tissue for treatment of various diseases, such as bacterial vaginosis, or for prophylaxis.
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申请公布号 |
US7456207(B2) |
申请公布日期 |
2008.11.25 |
申请号 |
US20040946133 |
申请日期 |
2004.09.22 |
申请人 |
TEVA PHARMACEUTICALS USA, INC. |
发明人 |
BENTLEY CHRISTINE LYNN;FELDTMOSE KAREN |
分类号 |
A01N43/50;A61F6/06;A61K9/00;A61K31/4164;A61K31/4178;A61K31/496;A61K31/715 |
主分类号 |
A01N43/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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