POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS EPIDERMIDIS
摘要
The present invention features polypeptides comprising an amino acid sequ ence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypept ide. The full-length naturally occurring polypeptide is referred to herein a s full-length ORF1319e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
申请公布号
CA2675992(A1)
申请公布日期
2008.11.20
申请号
CA20082675992
申请日期
2008.01.18
申请人
MERCK & CO., INC.
发明人
ANDERSON, ANNALIESA S.;MCNEELY, TESSIE;COOK, JAMES C., III;MONTGOMERY, DONNA L.;MCCLEMENTS, WILLIAM L.