发明名称 |
USE OF ANTI-CX3CR1 ANTIBODY, ANTI-FRACTALKINE ANTIBODY AND FRACTALKINE |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide uses of an antibody directed to X3CR1, and fractalkine. <P>SOLUTION: The identification, removal and separation of killer lymphocytes become easy by the anti-CX3CR1 antibody. Also, by inhibiting the interaction of the CX3CR1 with the fractalkine, it becomes possible to provide an antibody medicine for inhibiting the chemotaxis and cytotoxic activity of the killer lymphocytes. <P>COPYRIGHT: (C)2009,JPO&INPIT</p> |
申请公布号 |
JP2008278889(A) |
申请公布日期 |
2008.11.20 |
申请号 |
JP20080121030 |
申请日期 |
2008.05.07 |
申请人 |
EISAI R & D MANAGEMENT CO LTD |
发明人 |
IMAI TOSHIO;NISHIMURA MIYUKI;MURAMOTO KENZO;KUBOI YOSHIKAZU |
分类号 |
C12N5/10;A61K39/395;A61P1/16;A61P29/00;A61P37/02;C07K16/24;C07K16/28;G01N33/48;G01N33/53;G01N33/569 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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