| 摘要 |
Contemplated compositions, devices, and methods comprise immunodominant a ntigens from selected human pathogens (Burkholderia pseudomallei, Borrelia b urgdorferi, Brucella melitensis, Chlamydia muridarum, Coxiella burnetii, Fra ncisella tularensis, human Herpes virus 1 and 2, Mycobacterium tuberculosis, Plasmodium falciparum, and Vaccinia virus) can be used as a vaccine, as diag nostic markers, and as therapeutic agents. In particularly preferred aspects , the antigens have quantified and known relative reactivities with respect to sera of a population infected with the pathogen, and have a known associa tion with a disease parameter. |
