| 发明名称 |
PROPHYLACTIC AND THERAPEUTIC USE OF SIRTUIN INHIBITORS IN TNF-ALPHA MEDIATED PATHOLOGIES |
| 摘要 |
The invention relates to the use of sirtuin inhibitors for reducing TNF-alpha production by cells and organisms. The invention also concerns prophylactic and therapeutic applications of sirtuin inhibitors in TNF-alpha mediated pathologies, such as various inflammatory and autoimmune disorders. |
| 申请公布号 |
WO2008138943(A2) |
申请公布日期 |
2008.11.20 |
| 申请号 |
WO2008EP55880 |
申请日期 |
2008.05.14 |
| 申请人 |
UNIVERSITE LIBRE DE BRUXELLES;LEO, OBERDAN;GALLI, MARA;VAN GOOL, FREDERIC |
发明人 |
LEO, OBERDAN;GALLI, MARA;VAN GOOL, FREDERIC |
| 分类号 |
A61K31/166;A61K31/352;A61K31/353;A61K31/513;A61P7/06;A61P9/10;A61P17/06;A61P19/02;A61P19/06;A61P21/04;A61P25/16;A61P25/28;A61P31/18;A61P37/00;A61P37/08 |
主分类号 |
A61K31/166 |
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