发明名称 |
MUTANT ALLERGENS |
摘要 |
<p>Novel recombinant allergens with multiple mutations and reduced IgE binding affinity are disclosed. The allergens are non-naturally occurring mutants of naturally-occurring allergens. The overall PROPORTIONAL -carbon backbone tertiary structure is essentially preserved. Also disclosed is a method for preparing such recombinant allergens as well as uses thereof.</p> |
申请公布号 |
EP1373510(B1) |
申请公布日期 |
2008.11.19 |
申请号 |
EP20010996610 |
申请日期 |
2001.11.16 |
申请人 |
ALK-ABELLO A/S |
发明人 |
HOLM, JENS;IPSEN, HENRIK;NEDERGAARD LARSEN, JOERGEN;SPANGFORT, MICHAEL, DHO |
分类号 |
C12N15/29;G01N33/53;A61K38/11;A61K39/00;A61K39/35;A61K39/36;A61P37/08;C07K14/00;C07K14/415;C07K14/435;C07K16/16;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02 |
主分类号 |
C12N15/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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