发明名称 |
METHOD AND REAGENTS FOR TREATING HEPATIC FIBROSIS AND INFLAMMATION |
摘要 |
<p>The invention relates to methods for identifying an anti-fibrotic or anti-inflammatory agent comprising determining cathepsin S expression in activated hepatic stellate cells which have been exposed to a test compound and comparing expression to non-exposed hepatic stellate cells. The invention also relates to methods for treating a disorder characterised or caused by hepatic fibrosis or inflammation, comprising administering a cathepsin S inhibitor to a subject.</p> |
申请公布号 |
EP1991692(A2) |
申请公布日期 |
2008.11.19 |
申请号 |
EP20070748656 |
申请日期 |
2007.04.23 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
MAUBACH, GUNTER;ZHOU, LANG;LIM,MICHELLE CHIN CHIA |
分类号 |
C12Q1/37;A61K31/00;G01N33/50;G01N33/569;G01N33/68 |
主分类号 |
C12Q1/37 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|