发明名称 DIHYDROPYRIDINE DERIVATIVE FOR TREATING CANCER OR A PRE-CANCEROUS CONDITION AND OTHER CONDITIONS
摘要 <p>The use of dihydropyridine-5-phosphonic acid cyclic propylene ester derivatives of formula (I), a prodrug thereof, or a pharmaceutically acceptable salt of said compound or prodrug in the treatment of cancers, pre-cancerous conditions and other conditions is disclosed, wherein each of R&lt;SUB&gt;1&lt;/SUB&gt;-R&lt;SUB&gt;8&lt;/SUB&gt; are the same or different, are hydrogen or C&lt;SUB&gt;1&lt;/SUB&gt;-C&lt;SUB&gt;6&lt;/SUB&gt; alkyl; one of X&lt;SUB&gt;1&lt;/SUB&gt; and X&lt;SUB&gt;2&lt;/SUB&gt; is nitro while the other is hydrogen; each of Y&lt;SUB&gt;1&lt;/SUB&gt; and Y&lt;SUB&gt;2&lt;/SUB&gt; may be the same or different, is phenyl which may be substituted by chlorine, fluorine or alkoxy; and m and n are integers from 0-4, a prodrug thereof, or a pharmaceutically acceptable salt thereof.</p>
申请公布号 WO2008137107(A1) 申请公布日期 2008.11.13
申请号 WO2008US05731 申请日期 2008.05.02
申请人 KROUSE, ANDREW J. 发明人 KROUSE, ANDREW J.
分类号 A61K31/66;A01N57/10;A01N57/36 主分类号 A61K31/66
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