发明名称 |
System For the Production of Dimeric Proteins Based on the Transport System of Hemolysin of Escherichia Coli |
摘要 |
The system comprises a DNA construct comprising: a) a first nucleic acid sequence containing the nucleotide sequence coding for a product of interest; b) a second nucleic acid sequence containing the nucleotide sequence coding for a dimerization domain; and c) a third nucleic acid sequence containing the nucleotide sequence coding for Escherichia coli alpha-hemolysin (HlyA) or for a fragment of said protein comprising the recognition signal of the E. coli hemolysin (Hly) transport system secretion mechanism. It is applicable in producing recombinant dimeric proteins.
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申请公布号 |
US2008280346(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
US20040566827 |
申请日期 |
2004.07.19 |
申请人 |
DE LORENZO PRIETO VICTOR;FERNANDEZ HERRERO LUIS ANGEL |
发明人 |
DE LORENZO PRIETO VICTOR;FERNANDEZ HERRERO LUIS ANGEL |
分类号 |
C12N1/21;C07K14/195;C07K14/245;C07K16/00;C12N15/31;C12N15/62;C12N15/63;C12P21/02 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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