[6,6] AND [6,7]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS

摘要

Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. These novel compounds have the structure:formule (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein n₁, n₂, n₃, n₄, A, B, D, E, G, Y, Z, R₁ and R₂ are defined herein.