| 摘要 |
Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis. |
| 申请人 |
SUNESIS PHARMACEUTICALS, INC.;ALLEN, DARIN;AMERIKS, MICHAEL, K.;AXE, FRANK, U.;BURDETT, MATTHEW;CAI, HUI;CHOONG, INGRID;EDWARDS, JAMES, P.;LEW, WILLARD;MEDUNA, STEVEN, P. |
发明人 |
ALLEN, DARIN;AMERIKS, MICHAEL, K.;AXE, FRANK, U.;BURDETT, MATTHEW;CAI, HUI;CHOONG, INGRID;EDWARDS, JAMES, P.;LEW, WILLARD;MEDUNA, STEVEN, P. |
