发明名称 |
Novel P-Selectin Ligand Protein |
摘要 |
A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.
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申请公布号 |
US2008280327(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
US20080167680 |
申请日期 |
2008.07.03 |
申请人 |
GENETICS INSTITUTE, L.L.C. |
发明人 |
LARSEN GLENN R.;SAKO DIANNE S.;CHANG XIAO-JIA;VELDMAN GEERTRUIDA M.;CUMMING DALE;KUMAR RAVINDRA;SHAW GRAY |
分类号 |
C12N15/09;C12P21/00;A61K38/00;A61K39/00;A61P29/00;A61P35/04;C07H21/04;C07K14/19;C07K14/47;C07K14/51;C07K14/52;C07K14/54;C07K14/705;C07K16/18;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N9/10;C12N9/64;C12N15/12;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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