发明名称 |
METHOD AND DEVICE FOR NON-INVASIVE PRENATAL DIAGNOSIS |
摘要 |
Method for non- invasive prenatal diagnosis comprising the following step s: a. obtain a sample of an organic fluid having a high probability of conta ining foetal cells from a pregnant woman; b. enrich said sample of organic f luid in at least one population of cells comprising at least one type of foe tal nucleated cells; c. isolate at least one cell from among said at least o ne type of foetal nucleated cells; d. perform a genetic analysis on said at least one cell isolated from among said at least one type of foetal nucleate d cells in order to highlight at least one genetic characteristic of said at least one foetal nucleated cell suitable for permitting said diagnosis; whe rein the step of isolating at least one cell from among said at least one ty pe of foetal nucleated cells is performed by individually selecting single c ells in a microfluidic device designed for said purpose. |
申请公布号 |
CA2686338(A1) |
申请公布日期 |
2008.11.13 |
申请号 |
CA20082686338 |
申请日期 |
2008.05.02 |
申请人 |
SILICON BIOSYSTEMS S.P.A. |
发明人 |
MANARESI, NICOLO;GIORGINI, GIUSEPPE;MEDORO, GIANNI;FITTIPALDI, ANTONIO |
分类号 |
C12Q1/24;C12N5/071;C12M3/00;C12Q1/68;G01N15/10;G01N33/569 |
主分类号 |
C12Q1/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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