发明名称 CRYSTALLINE FORM OF THE ARGININE SALT OF PERINDOPRIL, PROCESS FOR PREPARING IT, AND PHARMACEUTICAL COMPOSITIONS COMPRISING IT
摘要 <p>Alpha crystalline form of perindopril arginine salt (I), characterized by the X-ray diffraction diagram on powder, measured by a diffractometer (copper anticathode) and exhibited a Bragg angle 2 theta, an interreticular distance (d), an intensity and a relative intensity, as given in table of the specification, is new. Alpha crystalline form of perindopril arginine salt of formula (I), characterized by the X-ray diffraction diagram on powder, measured by a diffractometer (copper anticathode) and exhibited a Bragg angle 2 theta, an interreticular distance (d), an intensity and a relative intensity, as given in table of the specification, is new. Independent claims are included for: (1) a composition comprising (I) in combination with inert and nontoxic vehicles; and (2) the preparation of (I). [Image] ACTIVITY : Cardiovascular-Gen; Hypotensive; Cardiant. MECHANISM OF ACTION : Angiotensin I converting enzyme inhibitor. No biological data given.</p>
申请公布号 EP1989182(A1) 申请公布日期 2008.11.12
申请号 EP20070731039 申请日期 2007.02.26
申请人 LES LABORATOIRES SERVIER 发明人 COQUEREL, GERARD;LEFEBVRE, LOIC;SOUVIE, JEAN-CLAUDE;AUTHOUART, PASCALE
分类号 C07D209/42;A61K31/403 主分类号 C07D209/42
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