发明名称 |
Site-specific labelling of proteins |
摘要 |
An in vivo method for labelling a protein having an N-terminal cysteine is disclosed. A probe comprising a thioester group and a detectable label is introduced into a cell expressing the N-terminal cysteine protein, allowing for the N-terminal cysteine to cleave the thioester bond and resulting in the label being covalently attached to the N-terminus of the protein by an amide bond.
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申请公布号 |
US7449558(B2) |
申请公布日期 |
2008.11.11 |
申请号 |
US20040977396 |
申请日期 |
2004.10.29 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE |
发明人 |
YAO SHAO QIN;YEO SU-YIN DAWN |
分类号 |
C07K1/13;C07K14/47;G01N33/53;G01N33/58 |
主分类号 |
C07K1/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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