发明名称 RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF BETA-CATENIN
摘要 The invention relates to oligomeric compounds (oligomers), which target beta-catenin mRNA in a cell, leading to reduced expression of beta-catenin. Reduction of beta-catenin expression is beneficial for a range of medical disorders, such as hyperproliferative diseases, including cancer. The invention provides therapeutic compositions comprising oligomers and methods for modulating the expression of beta-catenin using said oligomers, including methods of treatment.
申请公布号 WO2008132234(A2) 申请公布日期 2008.11.06
申请号 WO2008EP55365 申请日期 2008.04.30
申请人 SANTARIS PHARMA A/S;WORM, JESPER 发明人 WORM, JESPER
分类号 A61K31/7088;C12N15/113 主分类号 A61K31/7088
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