发明名称 OXIMYL HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS PROTEASE INHIBITOR
摘要 The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 US2008274082(A1) 申请公布日期 2008.11.06
申请号 US20080108653 申请日期 2008.04.24
申请人 GAI YONGHUA;SUN YING;OR YAT SUN;WANG ZHE 发明人 GAI YONGHUA;SUN YING;OR YAT SUN;WANG ZHE
分类号 A61K38/05;A61K38/21;A61P31/12;C07D207/02;C07D401/12;C07D405/12;C07D409/12 主分类号 A61K38/05
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