发明名称 |
Modulation of the Integrin Linked Kinase Signaling Pathway to Promote Cardiac Cell Proliferation and Self-Renewal |
摘要 |
Modulation of the integrin-linked kinase (ILK) signaling pathway is used to enhance the remodeling process relevant to a wide range of cardiac diseases. More specifically, a process to instigate beneficial human cardiac hypertrophy or for post myocardial infarction (MI) remodeling comprising illiciting an overexpression of ILK, is described. The ILK signaling pathway is also used as a means for cardiac stem cell proliferation and self-renewal
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申请公布号 |
US2008274491(A1) |
申请公布日期 |
2008.11.06 |
申请号 |
US20060915687 |
申请日期 |
2006.05.29 |
申请人 |
COLES JOHN G;HANNIGAN GREGORY;LU HUANZHANG |
发明人 |
COLES JOHN G.;HANNIGAN GREGORY;LU HUANZHANG |
分类号 |
C12N5/077;C12N15/861 |
主分类号 |
C12N5/077 |
代理机构 |
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代理人 |
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地址 |
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