PROPARGYLATED AMINOINDANS, PROCESSES FOR PREPARATION, AND USES THEREOF

摘要

This invention provides compounds having the structure (I) wherein R₁ is methyl and R₂ is H, or R₁ is ethyl and R₂ is hydroxymethyl; R₃ is H or propargyl; and R₄ is either H or t-butyloxycarbonyl; or an enantiomer or a pharmaceutically acceptable salt thereof. This invention further provides the use of a therapeutically effective amount of such compounds to treat a subject afflicted with a psychiatric disorder, Parkinson's disease, Alzheimer's disease, dementia, or a neurological disorder.