发明名称 Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
摘要 Disclosed is a compound of formula I, wherein R9 is optionally substituted aryl or benzyl, R11 is optionally substituted benzothiazolyl, X is N and Y is alkylene of 1-3 carbon atoms, and the remaining substituents are as defined in the specification. The compounds are useful for the treatment cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction.
申请公布号 NZ544449(A) 申请公布日期 2008.10.31
申请号 NZ20040544449 申请日期 2004.06.07
申请人 CV THERAPEUTICS, INC. 发明人 ZABLOCKI, JEFF;ELZEIN, ELFATIH;MARQUART, TIM
分类号 A61P9/06;C07D211/58;C07D277/64;C07D295/21;C07D417/12;(IPC1-7):C07D277/64;C07D295/20;A61K31/496 主分类号 A61P9/06
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