| 摘要 |
PROBLEM TO BE SOLVED: To provide a method of detecting an epstein-barr virus (EBV). SOLUTION: The present invention relates to peptides that are immunochemically reactive with antibodies to the Epstein-Barr virus (EBV), and includes at least a portion of VCA-p18 or VCA-p40 protein encoded within EBV open reading frames BFRF3 and BdRF1 respectively, or a functional variant thereof. The invention further relates to nucleic acid sequences encoding these peptides, monoclonal antibodies against these peptides, cell lines capable of producing monoclonal antibodies and anti-idiotype antibodies. The invention also relates to recombinant vector molecules including the nucleic acid sequence and host cells transformed or transfected with these vector molecules. The invention is further concerned with immunological reagents and methods for the detection of EBV or anti-EBV antibodies and a method for the amplification and detection of Epstein Barr viral nucleic acid. COPYRIGHT: (C)2009,JPO&INPIT
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