<p>A composition for use in bone healing and bone regeneration in the form of a viscoelastic hydrogel gel or liquid formulation comprising fibrinogen, thrombin and an inorganic component comprising a strontium (Sr) containing compound and/or possibly another metal such as a calcium containing compound. The strontium containing compound can be dissolved in the thrombin solutions or added to the clot in crystalline particulate form. Upon mixing the components, gelation takes place to form a matrix. The composition may also comprise an iodine-containing compound which acts as a plasticizer.</p>
申请公布号
WO2008131154(A2)
申请公布日期
2008.10.30
申请号
WO2008US60720
申请日期
2008.04.18
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A.;BARRY, JOHN, J.;GOESSL, ANDREAS;ZIMMER, GERALD