| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for accumulating and producing fine chemical materials (e.g., lysine) in a medium of an microorganism or the microorganism by increasing metabolic inflow through pentose phosphate route in the microorganism. <P>SOLUTION: A method for increasing generation of fine chemical materials such as lysine from a microorganism, e.g., a corynebacterium by deregulating a ferment-encoding gene, i.e., fructose-1,6-bisphosphatase, is provided. Further, a new method for producing lysine by regulating carbon inflow directing to oxaloacetic acid (OAA), is also provided. In one a preferable embodiment, a method for producing lysine by using fructose or sucrose as the carbon source is provided. <P>COPYRIGHT: (C)2009,JPO&INPIT |
